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Structure of a Clostridium botulinum C143S thiaminase I/thiamin complex reveals active site architecture,

Thiaminases are responsible for the degradation of thiamin and its metabolites. Two classes of thiaminases have been identified based on their three-dimensional structures and in their requirements for a nucleophilic second substrate. While the reactions of several thiaminases have been characterize...

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Main Authors: Sikowitz, Megan D., Shome, Brateen, Zhang, Yang, Begley, Tadhg P., Ealick, Steven E.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883099/
https://ncbi.nlm.nih.gov/pubmed/24079939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400841g
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