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Effects of Epinephrine, Adrenocorticotrophic Hormone, and Theophylline on Adenosine 3′,5′-Monophosphate Phosphodiesterase Activity in Fat Cells

When rat fat cells were incubated with ACTH, epinephrine, or theophylline for 2 to 10 min, cyclic AMP phosphodiesterase (3′:5′-cyclic-AMP 5′-nucleotidohydrolase, E.C. 3.1.4.17) activity (K(m) about 0.39 μM) in the 100,000 × g sediment fraction of homogenates was increased 35 to 50%. The effects of e...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Pawlson, L. G., Lovell-Smith, C. J., Manganiello, V. C., Vaughan, M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1974
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388292/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4365758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.1639
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