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Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation

A large proportion of vagal afferents are dependent on neurotrophin-3 (NT-3) for survival. NT-3 is expressed in developing gastrointestinal (GI) smooth muscle, a tissue densely innervated by vagal mechanoreceptors, and thus could regulate their survival. We genetically ablated NT-3 from developing G...

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Bibliografiset tiedot
Päätekijät: Fox, Edward A., Biddinger, Jessica E., Baquet, Zachary C., Jones, Kevin R., McAdams, Jennifer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882559/
https://ncbi.nlm.nih.gov/pubmed/24068045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00337.2013
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