Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca(2+)-induced ATP production in cardiac H9c2 myoblasts

Ca(+) influx to mitochondria is an important trigger for both mitochondrial dynamics and ATP generation in various cell types, including cardiac cells. Mitochondrial Ca(2+) influx is mainly mediated by the mitochondrial Ca(2+) uniporter (MCU). Growing evidence also indicates that mitochondrial Ca(2+...

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Detalhes bibliográficos
Main Authors: O-Uchi, Jin, Jhun, Bong Sook, Hurst, Stephen, Bisetto, Sara, Gross, Polina, Chen, Ming, Kettlewell, Sarah, Park, Jongsun, Oyamada, Hideto, Smith, Godfrey L., Murayama, Takashi, Sheu, Shey-Shing
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Energetics and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882548/
https://ncbi.nlm.nih.gov/pubmed/24124188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00094.2013
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