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Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN

AIM: To investigate the regulative effect of miRNA (miR)-221 on colorectal carcinoma (CRC) cell radiosensitivity and the underlying mechanisms. METHODS: A human CRC-derived cell line was cultured conventionally and exposed to different doses of X-rays (0, 2, 4, 6 and 8 Gy). The total RNA and protein...

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Autors principals: Xue, Qi, Sun, Kai, Deng, Hai-Jun, Lei, Shang-Tong, Dong, Jing-Qing, Li, Guo-Xin
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882403/
https://ncbi.nlm.nih.gov/pubmed/24409057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i48.9307
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