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Time-dependent modulation of GABA(A)-ergic synaptic transmission by allopregnanolone in locus coeruleus neurons of Mecp2-null mice
Rett syndrome (RTT) is a neurodevelopmental disorder with symptoms starting 6–18 mo after birth, while what underlies the delayed onset is unclear. Allopregnanolone (Allop) is a metabolite of progesterone and a potent modulator of GABA(A)-ergic currents whose defects are seen in RTT. Allop changes i...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882384/ https://ncbi.nlm.nih.gov/pubmed/24067915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00195.2013 |
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