Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains

Impaired glucose tolerance (IGT) and type 2 diabetes (T2DM) are polygenic disorders with complex pathophysiologies; recapitulating them with mouse models is challenging. Despite 70% genetic homology, C57BL/6J (BL6) and C57BLKS/J (BLKS) inbred mouse strains differ in response to diet- and genetic-ind...

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Hlavní autoři: Sims, Emily K., Hatanaka, Masayuki, Morris, David L., Tersey, Sarah A., Kono, Tatsuyoshi, Chaudry, Zunaira Z., Day, Kathleen H., Moss, Dan R., Stull, Natalie D., Mirmira, Raghavendra G., Evans-Molina, Carmella
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882376/
https://ncbi.nlm.nih.gov/pubmed/24169046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00366.2013
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