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Outlier-Based Identification of Copy Number Variations Using Targeted Resequencing in a Small Cohort of Patients with Tetralogy of Fallot

Copy number variations (CNVs) are one of the main sources of variability in the human genome. Many CNVs are associated with various diseases including cardiovascular disease. In addition to hybridization-based methods, next-generation sequencing (NGS) technologies are increasingly used for CNV disco...

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Détails bibliographiques
Auteurs principaux: Bansal, Vikas, Dorn, Cornelia, Grunert, Marcel, Klaassen, Sabine, Hetzer, Roland, Berger, Felix, Sperling, Silke R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882271/
https://ncbi.nlm.nih.gov/pubmed/24400131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085375
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