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Conformational Dynamics of the Partially Disordered Yeast Transcription Factor GCN4

Molecular dynamics (MD) simulations have been employed to study the conformational dynamics of the partially disordered DNA binding basic leucine zipper domain of the yeast transcription factor GCN4. We demonstrate that back-calculated NMR chemical shifts and spin-relaxation data provide complementa...

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Detalhes bibliográficos
Main Authors: Robustelli, Paul, Trbovic, Nikola, Friesner, Richard A., Palmer, Arthur G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882080/
https://ncbi.nlm.nih.gov/pubmed/24409105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400654r
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