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Conformational Dynamics of the Partially Disordered Yeast Transcription Factor GCN4

Molecular dynamics (MD) simulations have been employed to study the conformational dynamics of the partially disordered DNA binding basic leucine zipper domain of the yeast transcription factor GCN4. We demonstrate that back-calculated NMR chemical shifts and spin-relaxation data provide complementa...

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Autors principals: Robustelli, Paul, Trbovic, Nikola, Friesner, Richard A., Palmer, Arthur G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882080/
https://ncbi.nlm.nih.gov/pubmed/24409105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400654r
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