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Disentangling the effects of age and APOE on neuropathology and late life cognitive decline

Age and APOE are the most robust risk factors for dementia and cognitive decline, but the underlying neurobiology remains unclear. We examined the extent to which the hallmark pathologies of Alzheimer’s disease, Lewy body disease, and cerebrovascular diseases account for the association of age and A...

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Detalhes bibliográficos
Main Authors: Yu, Lei, Boyle, Patricia A., Leurgans, Sue, Schneider, Julie A., Bennett, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882071/
https://ncbi.nlm.nih.gov/pubmed/24199961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.10.074
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