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Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome

Fetal valproate syndrome (FVS) is caused by in utero exposure to the drug sodium valproate. Valproate is used worldwide for the treatment of epilepsy, as a mood stabiliser and for its pain-relieving properties. In addition to birth defects, FVS is associated with an increased risk of autism spectrum...

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Detalhes bibliográficos
Main Authors: Jacob, John, Ribes, Vanessa, Moore, Steven, Constable, Sean C., Sasai, Noriaki, Gerety, Sebastian S., Martin, Darren J., Sergeant, Chris P., Wilkinson, David G., Briscoe, James
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882053/
https://ncbi.nlm.nih.gov/pubmed/24135485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013219
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