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The unfolded protein response has a protective role in yeast models of classic galactosemia
Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered by galactose in two yeast models of galactosemia:...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882048/ https://ncbi.nlm.nih.gov/pubmed/24077966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012641 |
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