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Mechanisms of protein-folding diseases at a glance

For a protein to function appropriately, it must first achieve its proper conformation and location within the crowded environment inside the cell. Multiple chaperone systems are required to fold proteins correctly. In addition, degradation pathways participate by destroying improperly folded protei...

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Detalhes bibliográficos
Main Authors: Valastyan, Julie S., Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882043/
https://ncbi.nlm.nih.gov/pubmed/24396149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013474
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