Resistance in Pediatric Patients Experiencing Virologic Failure with First- and Second-Line Antiretroviral Therapy

We examined HIV-1 resistance in children failing first-and second-line antiretroviral therapy (ART) in South Africa, all with clade C virus. Those exposed to full-dose ritonavir had multiple protease resistance mutations. Nineteen percent had wild type virus. Appropriate ART sequencing in sub-Sahara...

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Hauptverfasser: Orrell, Catherine, Levison, Julie, Ciaranello, Andrea, Bekker, Linda-Gail, Kuritzkes, Daniel R., Freedberg, Kenneth A., Wood, Robin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881960/
https://ncbi.nlm.nih.gov/pubmed/23303240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0b013e3182829092
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