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Microtubules from Mammalian Brain: Some Properties of Their Depolymerization Products and a Proposed Mechanism of Assembly and Disassembly

Depolymerization products of purified microtubules from porcine brain were examined by sedimentation analysis and electron microscopy. The complete depolymerization mixture exhibited 36S and 6S components in concentration-dependent equilibrium, whether depolymerization was caused by low temperature...

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Main Authors: Kirschner, Marc W., Williams, Robley C., Weingarten, Murray, Gerhart, John C.
Format: Artigo
Jezik:Inglês
Izdano: 1974
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC388183/
https://ncbi.nlm.nih.gov/pubmed/4524627
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