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Accumulation of 5-Oxoproline in Mouse Tissues After Inhibition of 5-Oxoprolinase and Administration of Amino Acids: Evidence for Function of the γ-Glutamyl Cycle

5-Oxoprolinase catalyzes the conversion of 5-oxo-L-proline (L-pyroglutamate, L-2-pyrrolidone-5-carboxylate) to L-glutamate with concomitant stoichiometric cleavage of ATP to ADP and inorganic orthophosphate. In this reaction, a step in the γ-glutamyl cycle, 5-oxoproline (formed by the action of γ-gl...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Van Der Werf, Paul, Stephani, Ralph A., Meister, Alton
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1974
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4151516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.4.1026
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