Gene-Gene Interaction Between CCR3 and Eotaxin Genes: The Relationship With Blood Eosinophilia in Asthma

PURPOSE: Eosinophils function as an effector cell in the development of asthma and allergic disease. Eotaxins are cytokines that promote pulmonary eosinophilia via the receptor CCR3. Single-nucleotide polymorphisms (SNPs) in CCR3 and eotaxin genes are associated with asthma. In this study, genetic i...

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Bibliographic Details
Main Authors: Lee, June-Hyuk, Jang, An-Soo, Park, Sung-Woo, Kim, Do-Jin, Park, Choon-Sik
Format: Artigo
Language:Inglês
Published: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881401/
https://ncbi.nlm.nih.gov/pubmed/24404394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2014.6.1.55
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