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The Isolation of Simian Virus 40 Variants with Specifically Altered Genomes

Serial passage of simian virus 40 (SV40) at high multiplicity of infection leads to the emergence of variants with deleted, substituted, and/or duplicated DNA. Individual variants have been cloned by selective complementation with temperature sensitive SV40 mutants, or nonselectively by coinfection...

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Detalhes bibliográficos
Main Authors: Brockman, William W., Nathans, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388133/
https://ncbi.nlm.nih.gov/pubmed/4362640
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