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Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles()

The camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

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Detalhes bibliográficos
Main Authors: Venditto, Vincent J., Allred, Kimberly, Allred, Clinton D., Simanek, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881288/
https://ncbi.nlm.nih.gov/pubmed/19753350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b911353c
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