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Immune response to mutant neo-antigens: Cancer's lessons for aging

Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune response...

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Detalhes bibliográficos
Main Authors: Geyer, Rory J, Tobet, Rebecca, Berlin, Richard D, Srivastava, Pramod K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881104/
https://ncbi.nlm.nih.gov/pubmed/24404425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26382
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