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Immune response to mutant neo-antigens: Cancer's lessons for aging
Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune response...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881104/ https://ncbi.nlm.nih.gov/pubmed/24404425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26382 |
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