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Immune response to mutant neo-antigens: Cancer's lessons for aging

Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune response...

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書目詳細資料
Main Authors: Geyer, Rory J, Tobet, Rebecca, Berlin, Richard D, Srivastava, Pramod K
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881104/
https://ncbi.nlm.nih.gov/pubmed/24404425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26382
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