Cross-protective effect of a combined L5 plus L3 Leishmania major ribosomal protein based vaccine combined with a Th1 adjuvant in murine cutaneous and visceral leishmaniasis

BACKGROUND: Two Leishmania major ribosomal proteins L3 (LmL3) and L5 (LmL5) have been described as protective molecules against cutaneous leishmaniasis due to infection with L. major and Leishmania braziliensis in BALB/c mice when immunized with a Th1 adjuvant (non-methylated CpG-oligodeoxynucleotid...

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Detalhes bibliográficos
Main Authors: Ramirez, Laura, Corvo, Laura, Duarte, Mariana C, Chávez-Fumagalli, Miguel A, Valadares, Diogo G, Santos, Diego M, de Oliveira, Camila I, Escutia, Marta R, Alonso, Carlos, Bonay, Pedro, Tavares, Carlos AP, Coelho, Eduardo AF, Soto, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880976/
https://ncbi.nlm.nih.gov/pubmed/24382098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-7-3
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