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Persistence of O6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

The nervous system specificity of the carcinogenic effect of N-ethyl-N-nitrosourea in rats at the perinatal age is of particular interest because the formation of the ultimate reactant, an electrophilic ethyl cation, occurs nonenzymatically and, hence, is not tissue specific. Indeed, similar initial...

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Hlavní autoři: Goth, Regine, Rajewsky, Manfred F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1974
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC388067/
https://ncbi.nlm.nih.gov/pubmed/4522778
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