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Evaluating non-coding nucleotide repeat expansions in amyotrophic lateral sclerosis

Intermediate-length polyglutamine expansions in ataxin 2 are a risk factor for ALS. The polyglutamine tract is encoded by a trinucleotide repeat in a coding region of the ataxin 2 gene (ATXN2). Non-coding nucleotide repeat expansions in several genes are also associated with neurodegenerative and ne...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Figley, Matthew D., Thomas, Anna, Gitler, Aaron D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880650/
https://ncbi.nlm.nih.gov/pubmed/24269018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.09.024
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