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Highly-Substituted Enantioenriched Cyclopentane Derivatives by Palladium-Catalyzed [3+2] Trimethylenemethane Cycloadditions with Disubstituted Nitroalkenes

[Image: see text] β,β-Disubstituted nitroalkenes readily undergo palladium-catalyzed [3+2] cycloaddition with trimethylenemethane to generate nitrocyclopentanes in excellent yield and enantioselectivity. The reaction provides access to heavily substituted cyclopentanes containing up to three contigu...

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Detalhes bibliográficos
Main Authors: Trost, Barry M., Bringley, Dustin A., O'Keefe, B. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880620/
https://ncbi.nlm.nih.gov/pubmed/24161190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402487s
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