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Analysis of Heat-Labile Sites Generated by Reactions of Depleted Uranium and Ascorbate in Plasmid DNA

The goal of this study was to characterize how depleted uranium (DU) causes DNA damage. Procedures were developed to assess the ability of organic and inorganic DNA adducts to convert to single strand breaks (SSB) in pBR322 plasmid DNA in the presence of heat or piperidine. DNA adducts formed by met...

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Detalhes bibliográficos
Main Authors: Wilson, Janice, Young, Ashley, Civitello, Edgar R., Stearns, Diane M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880606/
https://ncbi.nlm.nih.gov/pubmed/24218036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-1057-6
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