Evolution of the Chalcone Isomerase Fold from Fatty Acid-Binding to Stereospecific Enzyme

Specialized metabolic enzymes biosynthesize chemicals of ecological importance, often sharing a pedigree with primary metabolic enzymes(1). However, the lineage of the enzyme chalcone isomerase (CHI) remained a quandary. In vascular plants, CHI-catalyzed conversion of chalcones to chiral (S)-flavano...

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Bibliografski detalji
Glavni autori: Ngaki, Micheline N., Louie, Gordon V., Philippe, Ryan N., Manning, Gerard, Pojer, Florence, Bowman, Marianne E., Li, Ling, Larsen, Elise, Wurtele, Eve Syrkin, Noel, Joseph P.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880581/
https://ncbi.nlm.nih.gov/pubmed/22622584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11009
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