Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats

BACKGROUND AND AIMS: Phosphatase and tensin homolog (PTEN) is a phosphoinositide phosphatase that regulates crucial cellular functions, including insulin signaling, lipid and glucose metabolism, as well as survival and apoptosis. Silymarin is the active ingredient in milk thistle and exerts numerous...

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Main Authors: Cheng, Kai-Chun, Asakawa, Akihiro, Li, Ying-Xiao, Chung, Hsien-Hui, Amitani, Haruka, Ueki, Takatoshi, Cheng, Juei-Tang, Inui, Akio
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880317/
https://ncbi.nlm.nih.gov/pubmed/24404172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084550
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