Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats

BACKGROUND AND AIMS: Phosphatase and tensin homolog (PTEN) is a phosphoinositide phosphatase that regulates crucial cellular functions, including insulin signaling, lipid and glucose metabolism, as well as survival and apoptosis. Silymarin is the active ingredient in milk thistle and exerts numerous...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Kai-Chun, Asakawa, Akihiro, Li, Ying-Xiao, Chung, Hsien-Hui, Amitani, Haruka, Ueki, Takatoshi, Cheng, Juei-Tang, Inui, Akio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880317/
https://ncbi.nlm.nih.gov/pubmed/24404172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084550
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