T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses: Implications for Restriction of HIV Replication

HIV infects key cell types of the immune system, most notably macrophages and CD4+ T cells. Whereas macrophages represent an important viral reservoir, activated CD4+ T cells are the most permissive cell types supporting high levels of viral replication. In recent years, it has been appreciated that...

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Autori principali: Berg, Randi K., Rahbek, Stine H., Kofod-Olsen, Emil, Holm, Christian K., Melchjorsen, Jesper, Jensen, David G., Hansen, Anne Louise, Jørgensen, Louise B., Ostergaard, Lars, Tolstrup, Martin, Larsen, Carsten S., Paludan, Søren R., Jakobsen, Martin R., Mogensen, Trine H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880311/
https://ncbi.nlm.nih.gov/pubmed/24404168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084513
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