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Effect of 5-Bromodeoxyuridine on Chromatin Transcription in Confluent Fibroblasts

3T6 mouse fibroblasts were grown in 5-bromodeoxyuridine (BrdU) so that approximately 20% of the thymine residues in DNA were replaced by BrdU. BrdU replacement caused an alteration in the relative incorporation of labeled nucleotide precursors into RNA. The RNA synthesized by cells grown in BrdU has...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hill, Bridget T., Tsuboi, Atsushi, Baserga, Renato
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4592691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.2.455
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