UGT1A1 Genotype-guided Phase I Study of Irinotecan, Oxaliplatin, and Capecitabine

PURPOSE: We performed a UGT1A1 genotype-guided study to determine the maximum tolerated dose (MTD) and evaluate the toxicities and pharmacokinetics of the combination of capecitabine (CAP), oxaliplatin (OX), and irinotecan (IRIN). EXPERIMENTAL DESIGN: Patients were screened for UGT1A1 *28 genotype p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Goetz, Matthew P., McKean, Heidi A., Reid, Joel M, Mandrekar, Sumithra J., Tan, Angelina D., Kuffel, Mary A., Safgren, Stephanie L., McGovern, Renee M., Goldberg, Richard M., Grothey, Axel A., McWilliams, Robert, Erlichman, Charles, Ames, Matthew M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880122/
https://ncbi.nlm.nih.gov/pubmed/24114122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-0034-9
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia