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Progesterone Receptor Membrane Component 1 as the Mediator of the Inhibitory Effect of Progestins on Cytokine-Induced Matrix Metalloproteinase 9 Activity In Vitro

Progesterone (P4) and the progestin, 17α-hydroxyprogesterone caproate, are clinically used to prevent preterm births (PTBs); however, their mechanism of action remains unclear. Cytokine-induced matrix metalloproteinase 9 (MMP-9) activity plays a key role in preterm premature rupture of the membranes...

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Detalles Bibliográficos
Main Authors: Allen, Terrence K., Feng, Liping, Grotegut, Chad A., Murtha, Amy P.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879993/
https://ncbi.nlm.nih.gov/pubmed/23813454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113493514
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