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Why Are Genes Encoded on the Lagging Strand of the Bacterial Genome?
Genomic DNA is used as the template for both replication and transcription, whose machineries may collide and result in mutagenesis, among other damages. Because head-on collisions are more deleterious than codirectional collisions, genes should be preferentially encoded on the leading strand to avo...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879979/ https://ncbi.nlm.nih.gov/pubmed/24273314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evt193 |
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