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Genomic, RNAseq, and Molecular Modeling Evidence Suggests That the Major Allergen Domain in Insects Evolved from a Homodimeric Origin

The major allergen domain (MA) is widely distributed in insects. The crystal structure of a single Bla g 1 MA revealed a novel protein fold in which the fundamental structure was a duplex of two subsequences (monomers), which had diverged over time. This suggested that the evolutionary origin of the...

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Bibliografski detalji
Glavni autori: Randall, Thomas A., Perera, Lalith, London, Robert E., Mueller, Geoffrey A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879970/
https://ncbi.nlm.nih.gov/pubmed/24253356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evt182
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