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Design of small-molecule epigenetic modulators

The field of epigenetics has expanded rapidly to reveal multiple new targets for drug discovery. The functional elements of the epigenomic machinery can be catagorized as writers, erasers and readers, and together these elements control cellular gene expression and homeostasis. It is increasingly cl...

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Detalhes bibliográficos
Main Authors: Pachaiyappan, Boobalan, Woster, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879946/
https://ncbi.nlm.nih.gov/pubmed/24300735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.11.001
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