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STAT3: the “Achilles” heel for AML?

In this issue of Blood, in a series of elegant studies in a transplantable mouse model of acute myeloid leukemia (AML), Hossain et al(1) show that systemic signal transducer and activator of transcription 3 (STAT3) blocking/TLR9 triggering can eradicate established AML through an immune-mediated mec...

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Bibliografiske detaljer
Main Authors: Rezvani, Katayoun, Barrett, John
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879899/
https://ncbi.nlm.nih.gov/pubmed/24385491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-537092
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