Transformation by Simian Virus 40 of Spleen Cells from a Hyperimmune Rabbit: Evidence for Synthesis of Immunoglobulin by the Transformed Cells

Spleen cells derived from a rabbit hyperimmunized with a Type III pneumococcal vaccine were exposed to simian virus 40 in vitro. After 114 days, transformed cells growing on the surface of one culture dish were observed and a cell line was established. The transformed cells had a morphology characte...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Collins, J. J., Black, P. H., Strosberg, A. D., Haber, E., Bloch, K. J.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1974
Sujets:	Biological Sciences: Immunology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387981/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4150020/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.2.260
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