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Assessment of HER2 status in breast cancer: overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: a quality control study

BACKGROUND: The gold standard of HER2 status assessment in breast cancer is still debated. Immunohistochemistry (IHC) and in-situ technology as fluorescent-labeled methodology (FISH) can be influenced by pre-analytical factors, assay-conditions and interpretation of test results. We retrospectively...

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Detalhes bibliográficos
Main Authors: Varga, Zsuzsanna, Noske, Aurelia, Ramach, Constanze, Padberg, Barbara, Moch, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879657/
https://ncbi.nlm.nih.gov/pubmed/24377754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-615
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