A Human Proteome Microarray Identifies that the Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Recognizes the 5′ Terminal Sequence of the Hepatitis C Virus RNA

Stem-loop I (SL1) located in the 5′ untranslated region of the hepatitis C virus (HCV) genome initiates binding to miR-122, a microRNA required for hepatitis HCV replication. However, proteins that bind SL1 remain elusive. In this study, we employed a human proteome microarray, comprised of ∼17,000...

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Detalhes bibliográficos
Main Authors: Fan, Baochang, Lu, Kuan-Yi, Reymond Sutandy, F. X., Chen, Yi-Wen, Konan, Kouacou, Zhu, Heng, Kao, C. Cheng, Chen, Chien-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879632/
https://ncbi.nlm.nih.gov/pubmed/24113282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.031682
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