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Extensive Post-translational Modification of Active and Inactivated Forms of Endogenous p53

The p53 tumor suppressor protein accumulates to very high concentrations in normal human fibroblasts infected by adenovirus type 5 mutants that cannot direct assembly of the viral E1B 55-kDa protein-containing E3 ubiquitin ligase that targets p53 for degradation. Despite high concentrations of nucle...

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Detalhes bibliográficos
Main Authors: DeHart, Caroline J., Chahal, Jasdave S., Flint, S. J., Perlman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879606/
https://ncbi.nlm.nih.gov/pubmed/24056736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.030254
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