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Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells
HER2 is an oncogenic tumor-associated antigen overexpressed in 20-25% of breast cancers, which is associated with increased invasion, metastasis of the disease and resistance to therapy. Recent studies have further shown that HER2 can increase the population of breast cancer stem cells (BCSCs). Howe...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879588/ https://ncbi.nlm.nih.gov/pubmed/24391448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.6309 |
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