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Intestinal Cell Proliferation and Senescence Are Regulated by Receptor Guanylyl Cyclase C and p21
Guanylyl cyclase C (GC-C) is expressed in intestinal epithelial cells and serves as the receptor for bacterial heat-stable enterotoxin (ST) peptides and the guanylin family of gastrointestinal hormones. Activation of GC-C elevates intracellular cGMP, which modulates intestinal fluid-ion homeostasis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879579/ https://ncbi.nlm.nih.gov/pubmed/24217248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511311 |
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