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Strong Heterogeneity in Mutation Rate Causes Misleading Hallmarks of Natural Selection on Indel Mutations in the Human Genome

Elucidating the mechanisms of mutation accumulation and fixation is critical to understand the nature of genetic variation and its contribution to genome evolution. Of particular interest is the effect of insertions and deletions (indels) on the evolution of genome landscapes. Recent population-scal...

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Detalhes bibliográficos
Main Authors: Kvikstad, Erika M., Duret, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879449/
https://ncbi.nlm.nih.gov/pubmed/24113537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst185
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