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The Characterization of Sponge NLRs Provides Insight into the Origin and Evolution of This Innate Immune Gene Family in Animals

The “Nucleotide-binding domain and Leucine-rich Repeat” (NLR) genes are a family of intracellular pattern recognition receptors (PRR) that are a critical component of the metazoan innate immune system, involved in both defense against pathogenic microorganisms and in beneficial interactions with sym...

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Detalhes bibliográficos
Main Authors: Yuen, Benedict, Bayes, Joanne M., Degnan, Sandie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879445/
https://ncbi.nlm.nih.gov/pubmed/24092772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst174
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