Common TLR1 Genetic Variation Is Not Associated with Death from Melioidosis, a Common Cause of Sepsis in Rural Thailand

Melioidosis, infection caused by the Gram-negative bacterium Burkholderia pseudomallei, is a common cause of sepsis in northeast Thailand. In white North Americans, common functional genetic variation in TLR1 is associated with organ failure and death from sepsis. We hypothesized that TLR1 variants...

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Detalhes bibliográficos
Main Authors: Chantratita, Narisara, Tandhavanant, Sarunporn, Myers, Nicolle D., Chierakul, Wirongrong, Wuthiekanun, Vanaporn, Mahavanakul, Weera, Limmathurotsakul, Direk, Peacock, Sharon J., West, T. Eoin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879377/
https://ncbi.nlm.nih.gov/pubmed/24392083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083285
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