DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

Pathogen-associated molecular patterns (PAMPs) trigger host immune response by activating pattern recognition receptors like toll-like receptors (TLRs). However, the mechanism whereby several pathogens, including viruses, activate TLRs via a non-PAMP mechanism is unclear. Endogenous “inflammatory me...

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Detalhes bibliográficos
Main Authors: Tsai, Su-Yu, Segovia, Jesus A., Chang, Te-Hung, Morris, Ian R., Berton, Michael T., Tessier, Philippe A., Tardif, Mélanie R., Cesaro, Annabelle, Bose, Santanu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879357/
https://ncbi.nlm.nih.gov/pubmed/24391503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003848
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