Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

Innate cytokine response provides the first line of defense against influenza virus infection. However, excessive production of cytokines appears to be critical in the pathogenesis of influenza virus. Interferon lambdas (IFN-λ) have been shown to be overproduced during influenza virus infection, but...

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Detalhes bibliográficos
Main Authors: Wei, Haitao, Wang, Song, Chen, Qinghuang, Chen, Yuhai, Chi, Xiaojuan, Zhang, Lianfeng, Huang, Shile, Gao, George F., Chen, Ji-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879354/
https://ncbi.nlm.nih.gov/pubmed/24391501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003845
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