A technique for quantifying intracellular free sodium ion using a microplate reader in combination with sodium-binding benzofuran isophthalate and probenecid in cultured neonatal rat cardiomyocytes

BACKGROUND: Intracellular sodium ([Na(+)](i)) kinetics are involved in cardiac diseases including ischemia, heart failure, and hypertrophy. Because [Na(+)](i) plays a crucial role in modulating the electrical and contractile activity in the heart, quantifying [Na(+)](i) is of great interest. Using f...

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Библиографические подробности
Главные авторы: Katoh, Daisuke, Hongo, Kenichi, Ito, Keiichi, Yoshino, Takuya, Kayama, Yosuke, Komukai, Kimiaki, Kawai, Makoto, Date, Taro, Yoshimura, Michihiro
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Technical Note
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879185/
https://ncbi.nlm.nih.gov/pubmed/24369990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-556
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