Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles

BACKGROUND: Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) that associate with clinical phenotypes, but these SNPs usually explain just a small part of the heritability and have relatively modest effect sizes. In contrast, SNPs that associat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Dharuri, Harish, Henneman, Peter, Demirkan, Ayse, van Klinken, Jan Bert, Mook-Kanamori, Dennis Owen, Wang-Sattler, Rui, Gieger, Christian, Adamski, Jerzy, Hettne, Kristina, Roos, Marco, Suhre, Karsten, Van Duijn, Cornelia M, van Dijk, Ko Willems, 't Hoen, Peter AC
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879060/
https://ncbi.nlm.nih.gov/pubmed/24320595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-865
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk