Prevention of Pneumococcal Disease in Mice Immunized with Conserved Surface-Accessible Proteins

The development of a vaccine against Streptococcus pneumoniae has been complicated by the existence of at least 90 antigenically distinct capsular serotypes. Common protein-based vaccines could represent the best strategy to prevent pneumococcal infections, regardless of serotype. In the present stu...

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Autori principali: Hamel, Josée, Charland, Nathalie, Pineau, Isabelle, Ouellet, Catherine, Rioux, Stéphane, Martin, Denis, Brodeur, Bernard R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC387903/
https://ncbi.nlm.nih.gov/pubmed/15102774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2659-2670.2004
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